Boneset: A Powerful Herb with a Fascinating History

Boneset (Eupatorium perfoliatum) is a remarkable herb with a rich history and diverse applications.

boneset - ohremedies


  • Boneset, scientifically known as Eupatorium perfoliatum, is a perennial plant native to eastern North America.
  • Used by Native Americans for centuries, boneset earned its name due to its distinctive leaves appearing to be pierced by the stem.


Historical Significance:

  • During the devastating “Spanish Flu” pandemic of 1918, boneset emerged as a powerful remedy, alleviating symptoms and preventing pulmonary complications.
  • Employed by Eclectic physicians, boneset played a crucial role in combating influenza and promoting overall wellness.

Traditional Uses:

  • Boneset is highly effective in breaking fevers, relieving pain and inflammation, and supporting immune function.
  • It has been traditionally used to treat colds, flu, fever, rheumatism, and arthritis.

Scientific Evidence:

  • Studies have confirmed boneset’s effectiveness in treating the common cold and flu, reducing symptoms and promoting recovery.
  • Its phytochemical composition provides anti-inflammatory, antioxidant, and immune-boosting effects.

Safety Concerns:

  • While boneset contains pyrrolizidine alkaloids (PAs), which are considered potentially toxic, its traditional dosage range ensures safety.
  • When consumed within recommended limits, boneset poses no risk of hepatotoxicity (liver toxicity).

Dosage and Medicinal Uses:

  • Boneset can be consumed as a tea, tincture, or capsule, with typical doses ranging from 20-60 drops of tincture or 60-120 mL of infusion, three times daily.
  • Its primary uses include breaking fevers, relieving pain and inflammation, and supporting respiratory health.


Boneset’s long history of medicinal use, coupled with its diverse therapeutic benefits, makes it an invaluable herb in natural medicine. As we continue to explore its potential, boneset remains a promising ally in promoting overall health and wellness, particularly in the face of pandemics.

Let’s keep exploring the potential of this remarkable plant to tackle future health challenges!

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